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Prostate Cancer: Dickinson Group

Research into cancer genetics is aimed at understanding the genes contributing to the development of different types of cancers. At present our group is studying genetic susceptibility to prostate cancer and blood cancers.

Parent Theme:

Cancer Research

The Identification of Genes Underlying Susceptibility to Prostate Cancer

Characterisation of Alpha 2 Integrin: A Potential Biomarker for Prostate Cancer

Regulation of the ITGA2 Gene by Methylation in Prostate Cancer

National Health and Medical Research Council

Australian Cancer Research Foundation

Cancer Australia

The Cancer Council Tasmania

Max Bruce Trust

Tasmanian Community Fund

Perpetual Trustees

Royal Hobart Hospital Research Foundation

Senior Members

Professor Simon Foote (Director)

Members

Dr Joanne Dickinson (Senior Research Fellow & Member)

Dr Jim Stankovich (Biostatistician & Member)

Team Members

Annette Banks (Genealogist)

James Marthick (Senior Technician - Genetics)

Dr Briony Patterson (Research Fellow)

Dr Russell Thomson (Biostatistician)

Local Collaborators

Dr Adele Holloway (Senior Research Fellow & Member)

Associate Professor Bruce Taylor (Principal Research Fellow)

Dr Ingrid van der Mei (Senior Research Fellow)

External Collaborators

Dr David Amor
Murdoch Childrens Research Institute

Dr Melanie Bahlo
Walter and Eliza Hall Institute

Professor Terry Dwyer

Professor John Hopper
University of Melbourne

Professor Kent Hunter

Dr James McKay

Professor Anne-Louise Ponsonby

Dr Melissa Southey

Professor Janet Stanford

*Dickinson JL, *Perera DI, *van der Mei IF, Ponsonby AL, *Polanowski AM, *Thomson RJ, *Taylor BV, McKay JD, *Stankovich JM, Dwyer T. Past environmental sun exposure and risk of multiple sclerosis: a role for a Vitamin D receptor polymorphism in this interaction. Multiple Sclerosis 2009 May;15(5):563-70.

Wray BN, *Stankovich J, Whittock L, Dwyer T, Ponsonby A-L, *van der Mei I, *Taylor B, *Dickinson J, *Foote S, *McMorran B. CTLA-4 and multiple sclerosis: The A49G single nucleotide polymorphism shows no association with multiple sclerosis in a Southern Australian population. Journal of Neuroimmunology 2008 196:139-142

*FitzGerald LM, *Patterson B, *Thomson R, *Polanowski A, *Quinn SJ, Brohede J, Thornton T, Challis DR, Mackey DA, Dwyer T, *Foote SJ, Hannan G, *Stankovich JM, McKay JD, *Dickinson JL. Identification of a prostate cancer susceptibility gene on chromosome 5p13q12 associated with risk of both familial and sporadic disease. European Journal of Human Genetics 2009;17(3):368-77

Dwyer T, *van der Mei IAF, Ponsonby AL, *Taylor BVM, *Stankovich JM, McKay JD, *Thomson RJ, *Polanowski A, *Dickinson JL. Melanocortin 1 receptor genotype, past environmental sun exposure, and risk of multiple sclerosis. Neurology 2008;71(8):583-589

*FitzGerald LM, *Thomson R, *Polanowski A, *Patterson B, McKay JD, *Stankovich JM, *Dickinson JL. Sequence variants of alpha-methylacyl-CoA racemase are associated with prostate cancer risk: a replication study in an ethnically homogeneous population. The Prostate 2008;68(13):1373-9

Dwyer T, *Blizzard L, *Patterson B, *Ponsonby AL, *Martin K, *Quinn S, Sale MM, *Richards SM, Morley R, Rich S, *Dickinson JL. Association between birth weight and adolescent systolic blood pressure in a caucasian birth cohort differs according to skin type, CRH promoter or 11beta-HSD2 genotype. Arch Dis Child. 2008 Sep;93(9):760-7.

*Thomson R, *Quinn S, McKay J, Silver J, Bahlo M, *Fitzgerald L, *Foote SJ, *Dickinson J, *Stankovich JM. The advantages of dense marker sets of linkage analysis with very large families. Human Genetics 2007;121:459-468

*Dickinson JL, Sale MM, Passmore A, *FitzGerald LM, Wheatley CM, Burdon K, Craig J, Tengtrisorn S, Carden SM, Maclean H, Mackey DA. Novel mutations in the NDP gene: contribution to Norrie Disease, Familial Exudative Vitreo retinopathy and retinopathy of prematurity. Clinical and Experimental Ophthalmology 2006; 34 (7): 682-688.

Burdon K, Wirth M, Mackey D, Russell-Eggitt IM, Craig J, Elder J, *Dickinson J, Sale M. A novel mutation in the Connexin 46 gene causes ahtosomal dominant congenital cataract with incomplete penetrance. Journal of Medical Genetics 2004; 41(8).

Flowers KP, Wirth GM, Mackey DA, Russell-Eggitt IM, Craig J, Elder J, *Dickinson JL, Sale MM. Prevalence of mutations of crystallin genes in paediatric cataract families in South-eastern Australia. British Journal of Ophthalmology 2004; 88(1):79-83.

* Denotes Menzies Researcher