Learning how to make long-range nerves - an important step for brain repair
Acquired brain injury caused by head trauma, stroke, infection, substance abuse or disease is a significant health issue, with approximately half of sufferers requiring daily care, as current treatments are unable to repair the damage. We are yet to identify a candidate cell type that could generate replacement projection neurons. The axons of projection neurons span large distances in order to transfer information between, and process information from, multiple brain regions. This research project builds on our discovery that new projection neurons are continuously added to the anterior piriform cortex of the adult mouse brain. We will test the hypothesis that local progenitor cells are stimulated to generate new neurons that are required for olfactory memory processing.
- Professor David Adams - RMIT University