Dr Stephen Richards
Phone:
(03) 6226 2673
Private Bag:
23, Hobart TAS 7000
Position:
University Associate
Fax:
(03) 6226 7704
Biography:
Dr Richards joined the Muscle Diabetes Research Group in 2000 after post-doctoral positions at the University of Melbourne, Baker Institute, and Alfred Hospital in Melbourne, and INSERM U390 in Montpellier, France, working on cardiac metabolism and preservation in normal and failing hearts. In addition to doing research with Menzies, Dr Richards teaches undergraduate biochemistry for the University of Tasmania School of Medicine, and coordinates Honours and post-graduate students doing research projects for Menzies.
Research Interests:
The Muscle Diabetes Research Group has developed techniques for measuring microvascular blood flow within muscle in humans and animals. Importantly, the group (including Professor Stephen Rattigan and Dr Michelle Keske) has shown muscle blood flow to be an important determinant of the sensitivity of muscle to insulin, and that reduced blood flow responses to insulin contribute to insulin resistance, and possibly the development of type 2 diabetes. Dr Richards' research aims to determine why the microvascular actions of insulin are impaired in insulin resistant animal models, and aims to find ways of enhancing muscle blood flow responses to insulin. Two current methods for achieving this focus on (i) the role of the adipocyte-derived hormone adiponectin, and (ii) augmenting the biochemical signalling used by insulin to increase muscle microvascular blood flow, namely the nitric oxide-cyclic GMP pathway, with a view to the development of novel therapeutics.
Related Publications
*Ponsonby AL, *Blizzard CL, *Pezic A, *Cochrane J, Ellis J, Morley R, *Dickinson JL, *Patterson B, Sale ML, *Richards SM, *Dwyer T. Adiposity gain during childhood, ACE I/D polymorphisms and metabolic outcomes. Obesity 2008; 16: 2141-2147.
* Denotes Menzies Researcher
% Denotes published under maiden name