Primary Progressive MS (PPMS) is a type of Multiple Sclerosis that affects 1 in 10 people with the disease, and for which current MS treatments are not effective. Little specific research has been done in PPMS and our understanding of the risk factors for this variant of MS is poor.
This study is a case-control study where the cases will be followed longer term.
The case-control study aims to examine whether the established risk factors for MS also hold in people with PPMS and whether we can identify novel risk factors for this group. The longitudinal component examines which factors are associated with disease progression in people with PPMS.
This project will improve the understanding of the aetiology of MS for PPMS, which will contribute to unravelling the mechanisms of PPMS and ultimately the development of treatments and interventions.
- Dr Steve Simpson Jr.
- Susan Dobson
- Professor Anne-Louise Ponsonby - Murdoch Children's Research Institute
- Dr Robyn Lucas - Australian National University